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A New RSV Shot For Infants Is In Short Supply

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NEW YORK – A new RSV vaccine for infants is in low supply, and US health officials have advised doctors to give the medicine first to babies most at risk of serious sickness.

According to a Monday evening recommendation from the Centers for Illness Control and Prevention, infants under 6 months old with chronic lung illness or other underlying disorders should be prioritized.

RSV, or respiratory syncytial virus, is a common cause of cold-like symptoms in young children that can be fatal. It is a seasonal virus widely reported in the southern United States and is predicted to spread further over the next month or two.

The new one-time shot contains a lab-created antibody that aids the immune system in fighting the virus. The medicine, known as Beyfortus, was developed by AstraZeneca and Sanofi.

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A New RSV Shot For Infants Is In Short Supply

The FDA authorized it in July, and the CDC recommended it for newborns born immediately before or during the RSV season and those less than 8 months old when the season begins. They also suggested a dose for those 8- to 19-month-olds at higher risk of serious illness.

It is available in 50-milligram and 100-milligram prefilled syringes. The higher doses are intended for larger, heavier newborns.

In a recent letter to state immunization administrators, the CDC stated that orders for shots placed through a programme that pays for vaccines for impoverished and uninsured children would be halted. The CDC issued a more general warning to clinicians in the United States on Monday.

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Sanofi said that demand, particularly for greater doses, “has been higher than anticipated.”

According to health experts, there needs to be more to safeguard all children eligible for the larger shots. According to CDC officials, smaller doses may also be in short supply during the current RSV season. According to the CDC, doctors should not use two smaller doses on larger infants to protect the supply of such vaccines.

According to agency authorities, certain youngsters may be eligible for palivizumab, an earlier RSV treatment. This medication necessitates monthly injections.

Doctors are also being asked to try to persuade pregnant women to receive a new RSV vaccine aimed at protecting babies. When this occurs, the baby does not require the antibody medication.

SOURCE – (AP)

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2023 China: WHO Seeks Data On ‘Pneumonia Clusters’ In Children

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The World Health Organization (WHO) has requested more information from China regarding “clusters of undiagnosed pneumonia” that are reportedly increasing among children in the country’s north.

According to non-state media reports, pediatric hospitals in several parts of China are overcrowded with unwell children.

Chinese officials blamed the lifting of Covid restrictions for an increase in flu-like symptoms this winter.

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The WHO is advising Chinese citizens to take preventative steps.

The UN health agency said in a statement that it requested further information on allegations of “clusters of undiagnosed pneumonia in children in northern China” in the media and from ProMed, a worldwide outbreak tracking system.

Pneumonia is a broad medical word for an infection and inflammation of the lungs. Various viruses, bacteria, or fungi can cause it.

Following the release of the WHO statement, the state-run Xinhua news agency published an item on Thursday in which officials from China’s National Health Commission (NHC) stated that they were paying particular attention to diagnosing and treating children with respiratory infections.

While talks of China and a wave of infection can make people nervous, recalling the Covid-19 pandemic, it’s an excellent procedure for the WHO to seek clarification. But the only way of understanding why this outbreak of illnesses has occurred is if Beijing responds.

It is also uncommon for the WHO to request further information from countries regarding a cluster of illnesses. They do it nearly every day.

Daily, a WHO professional staff sifts through hundreds of media reports and internal surveillance data on circulating diseases from countries. Experts then assess whether more information is required if it becomes a public health emergency of international concern.

However, it is unusual to request additional information public. Previously, this was done through private channels between the WHO and national health officials.

pneumonia

China: WHO Seeks Data On ‘Pneumonia Clusters’ In Children

The UN agency is undoubtedly concerned that people may be more wary of viruses reported in China after COVID-19. In the aftermath of the pandemic, the WHO is likewise attempting to be more transparent.

The UK’s Health Security Agency (UKHSA) stated it was carefully monitoring the situation.

According to the WHO, Northern China has recorded an “increase in influenza-like illness” since October, compared to the same period in the previous three years.

The Chinese NHC reported last week that various respiratory infections were rising nationwide, including influenza, COVID-19, mycoplasma pneumonia (a frequent bacterial infection affecting younger children), and respiratory syncytial virus (RSV).

Officials attributed the increase to the removal of COVID-19 limitations.

Other nations, like the United Kingdom and the United States, had similar increases in flu-like symptoms when pandemic restrictions were relaxed.

“China is likely experiencing a major wave of childhood respiratory infections now because this is the first winter after their lengthy lockdown,” said Prof Francois Balloux of the University College London Genetics Institute.

pneumonia

China: WHO Seeks Data On ‘Pneumonia Clusters’ In Children

Prof Paul Hunter of the University of East Anglia (UEA) stated that there is now insufficient data to establish a definitive diagnosis of what is causing the diseases.

“Overall, this does not sound like an epidemic caused by a novel [new] virus,” he continued. If that’s the case, I’d expect many more adult infections. The rare illnesses documented in adults point to pre-existing immunity from previous exposure.”

The WHO says it is unclear whether the reported pneumonia outbreak and the overall increase in respiratory diseases reported by Beijing are linked and has issued a formal request for more information.

It has encouraged Chinese citizens to take basic precautions such as getting vaccinated, wearing masks, and washing their hands.

SOURCE – (AP)

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Dogs Are Coming Down With An Unusual Respiratory Illness In Several US States

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Veterinary laboratories in multiple states are looking into an odd respiratory ailment in dogs and urging consumers to take simple precautions to keep their pets healthy while vets strive to figure out what’s wrong.

Oregon, Colorado, and New Hampshire have all experienced the infection, which has caused long-term respiratory problems and pneumonia and is resistant to medications. Coughing, sneezing, nasal or ocular discharge, and lethargy are all respiratory infection symptoms in dogs. Some cases of pneumonia advance quickly, causing dogs to become quite ill within 24 to 36 hours.

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Dogs Are Coming Down With An Unusual Respiratory Illness In Several US States

Since mid-August, the Oregon Department of Agriculture has reported more than 200 disease cases. It has urged pet owners to contact their veterinarian if their dog becomes ill and directed state vets to report cases as quickly as possible.

The agency is collaborating with state researchers and the United States Department of Agriculture’s National Veterinary Services Laboratory to determine the source of the infections.

According to Kurt Williams, director of Oregon State University’s Oregon Veterinary Diagnostic Laboratory, dogs have died. However, without a precise definition of the sickness or a test for it, he said it’s difficult to estimate how many people died from a severe form of the virus.

Williams’ message to dog owners was simple: “Don’t panic.” He also advised dog owners to keep their pets’ immunizations up to date, including those that protect against certain respiratory infections.

As they try to identify the culprit, labs around the country have been sharing their findings.

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Dogs Are Coming Down With An Unusual Respiratory Illness In Several US States

David Needle, senior veterinary pathologist at the University of New Hampshire’s New Hampshire Veterinary Diagnostic Laboratory, has been researching the unusual ailment for nearly a year.

His group and colleagues at the university’s Hubbard Center for Genome Research have examined samples from canines in Rhode Island, New Hampshire, and Massachusetts, and more will be arriving from Oregon, Colorado, and probably other states shortly.

He stated that his team has not witnessed a significant increase in the number of dogs dying from the sickness, but he nonetheless advised pet owners to “reduce contact with other dogs.”

SOURCE – (AP)

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Pepper X Marks The Spot As South Carolina Pepper Expert Scorches His Own Guinness Book Heat Record, 1.64 Million Scoville Units

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Fort Mill, South Carolina — Ed Currie, an authority on hot peppers from South Carolina who developed and cultivated the Carolina Reaper pepper variety, which is three times hotter than the majority of pepper sprays used by law enforcement to subdue misbehaving intruders, has surpassed his previous world record with a pepper that is three times hotter.

The Guinness Book of World Records officially proclaimed Pepper X the hottest pepper in the world on October 9. It surpassed the Reaper as the culmination of Alex Currie’s ten-year quest to develop a pepper that delivers “immediate, brutal heat.”

Currie stated that Pepper X warmed his heart the first time he tasted it.

The humidity pervaded me for three and a half hours. “Then cramps set in,” Currie, one of only five individuals to have consumed an entire Pepper X thus far, remarked. “Those cramps are dreadful.” I was in excruciating agony while lying flat on a marble wall in the rain for about an hour.”

The Scoville Heat Unit is the unit of measurement for chilies heat. Zero is tasteless, whereas a standard jalapeno pepper contains approximately 5,000 units. The habanero, which held the record for approximately 25 years, generally exceeds 100,000. According to the Guinness Book of World Records, 1.64 million units comprise the Carolina Reaper.

The all-time high for Pepper X is 2.69 million units on average. In contrast, the average quantity of pepper spray carried by law enforcement officers is approximately 1.6 million units. Bear spray is advertised at a quantity of 2.2 million units.

pepper x

Pepper X Marks The Spot As South Carolina Pepper Expert Scorches His Own Guinness Book Heat Record.

Since Currie last set the hottest pepper record in 2013 with the Carolina Reaper, a brilliant red knobby fruit with what enthusiasts call a scorpion tail, Pepper X has been in development. The objective was to create an exceptionally fiery pepper with a delicate flavor.

Pepper X, which is pale yellow, lacks the same shelf allure as the alternatives above and emits an earthy flavor when heated. It is a hybrid offspring of the Carolina Reaper and an unidentified pepper that Currie claims was “brusquely hot and sent to me by a friend from Michigan.”

The burn-causing chemical found in peppers, known as capsaicin, is related to arsenic but is considerably less hazardous and does not pose a threat unless pounds of it are ingested. However, capsaicin is perceived as a threat by the minds of humans and other mammals, which transmits a potent burning signal to the body. Due to their dissimilar reaction, birds can disperse pepper seeds while preserving the plant.

The secretion of dopamine and endorphins accompanies the searing sensation induced in humans. Currie, who devoted himself to pepper cultivation after overcoming alcohol and drug dependencies, views resurgence as a natural high. He distributes his chilies to medical researchers in the hope that they can be utilized to treat chronic pain or discomfort and cure disease.

papper x

Pepper X Marks The Spot As South Carolina Pepper Expert Scorches His Own Guinness Book Heat Record.

Currie has been fixated on acquiring the harshest pepper in the world for the past twenty years. From the first crossbreed experiment to the record, it took ten years to bring Pepper X to prominence, including five years of testing to establish that it was a distinct plant with a distinct fruit and documenting its average heat across generations and plants.

“We have addressed the subjects of genetics, chemistry, and botany,” he declared.

Currie, whose PuckerButt company is attempting to establish an empire of hot pepper sauces, stated that the past decade has also provided him with abundant business teachings. Much of the attention drawn to the Carolina Reaper needed to be more appropriate and profitable.

Currie permitted others to cultivate the peppers without safeguarding his concepts. His attorneys have tallied over 10,000 unauthorized products bearing the Carolina Reaper name or other intellectual property.

Currie safeguards Pepper X. He stated that seeds will be distributed once he is certain that his children, his employees, who are also seeking second opportunities, and their families can adequately benefit from his efforts.

pepper x

Pepper X Marks The Spot As South Carolina Pepper Expert Scorches His Own Guinness Book Heat Record.

“Everyone else benefited financially from the Reaper.” Currie stated, “It is now time for us to reap the rewards of the labour I exert.”

This includes dozens of fields throughout York County, covert greenhouses where Currie develops peppers to prevent their theft, and a PuckerButt location in Fort Mill where Currie creates dozens of moderate to fiery sauce concepts. Additionally, he exports his chilies to businesses around the world.

Controversy has surrounded extremely fiery food challenges since a chip manufacturer recalled its products after a teen’s death.

Currie desires that individuals consume peppers because he believes that the rush that follows the pain can be advantageous. He considers most hot pepper challenges to be stupid and warns pepper peekers against being overly ambitious and reaching for a Carolina Reaper or Pepper X too soon.

“Tolerance develops over time,” Currie further implied that additional pepper heat could be emanating from the chillers, fields, and laboratories, but he forbids fans, reporters, and even the bankers assisting in the expansion of his company from observing.

“Behold, is this the apex?” Currie remarked with a mischievous grin on his face regarding Pepper X. “It is not the pinnacle, Mr. [No],”

SOURCE – (AP)

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